The accurate and efficient detection of biomarker such as dopamine (DA) and alpha-fetoprotein (AFP) is crucial for clinical diagnosis, while the demand for materials with concurrent antibacterial activity remains urgent in medical and biological fields. In this study, a novel multifunctional PW₁₂@ZIF-67-Au (PZA) nanoreactor was successfully synthesized. This nanoreactor not only enables sensitive and reliable multivariate sensing of DA (a key neurotransmitter associated with neurological diseases) and AFP (a vital tumor marker for hepatocellular carcinoma), but also exhibits excellent antibacterial performance against common pathogenic bacteria like Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The research provides a promising integrated solution for biomolecular detection and antibacterial protection, laying a solid foundation for its potential applications in clinical diagnostic and related fields.

A new study in eGastroenterology links gut dysbiosis with severe steatosis in metabolic dysfunction–associated steatotic liver disease (MASLD). In a 61-patient cohort, those with the inflammation-linked Bact2 enterotype developed severe steatosis at lower thresholds. Adding microbiota status to standard clinical tools improved diagnostic accuracy from 80% to 90%, suggesting a path toward earlier detection and personalized care.

The international scientific and technological journal FlexTech, co-launched by Tsinghua University Press and Wiley, officially released its 2025 Issue 2.

Researchers demonstrated highly dispersed NaVO₃ nanoparticles, as a ^•CH₂Cl radical surface-confined coupling center, demonstrating its superior performance in the selective coupling of methyl chloride to synthesize vinyl chloride. By incorporating NaVO₃ onto the surface of CeO₂, the catalyst enables effective capture of ^•CH₂Cl radicals during the CH₃Cl oxidative pyrolysis and its subsequent conversion into C₂H₃Cl, achieving a C₂H₃Cl selectivity of 56.7% and a CH₃Cl conversion of 56.6% at 750 °C.

A research team has outlined how synthetic biology can accelerate discoveries in plant–microbe interactions, offering strategies to enhance disease resistance, engineer synthetic symbioses, and manipulate root microbiomes.

A research team has reviewed how machine learning (ML) is revolutionizing fermentation design and process optimization by providing powerful simulation and prediction tools.

A research team has proposed a new approach to improve photosynthesis by replacing the enzyme ribulose-1,5-bisphosphate carboxylase/oxidase (RuBisCO) with phosphoenolpyruvate carboxylase (PEPC).

In a study published in MedComm - Oncology, researchers report that the enzyme O-GlcNAc Transferase (OGT) plays a key role in driving liver cancer linked to Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD-HCC). The team found that OGT levels increase as the disease progresses. They also discovered that OGT modifies the tumor suppressor protein PTEN in a way that disrupts its normal function, this modification leads to PTEN degradation and reduced phospholipase activity, triggering a cancer-promoting signaling pathway and accelerating tumor growth. The findings suggest that targeting OGT could offer a new therapeutic approach for treating MASLD-related liver cancer.