New AI tool predicts how microbes survive in Earth’s saltiest habitats
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Oct-2026 01:16 ET (22-Oct-2026 05:16 GMT/UTC)
Researchers have developed SuSha, a multi-model ensemble learning tool that predicts a microorganism's salt tolerance directly from its genome. Trained on the amino acid composition of 123 bacterial and archaeal species and validated on 2,678 metagenomes from freshwater, marine, and hypersaline habitats worldwide, SuSha achieved over 90% accuracy for extreme halophiles. It offers a powerful way to study the more than 81% of microbes that cannot be cultured in the lab.
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