The Keck School of Medicine of USC and Keck Medicine of USC have launched collaborations with Tempus AI, Inc., a technology company at the forefront of applying AI to precision medicine, to integrate clinical care, clinical trials and research through a unified framework. The new framework intends to create an ongoing cycle of learning between patient care and research, with a primary goal of improving outcomes for the more than 1.5 million annual patient visits to Keck Medicine of USC hospitals and clinics. It is designed to promote more personalized and precise care to patients across the Keck Medicine of USC health system with tailored recommendations informed by large-scale clinical data. At the same time, it seeks to use clinical data to inform and accelerate research to develop innovative therapies and algorithms that may translate for public benefit. At the heart of the USC -Tempus collaboration is the pioneering research and patient care delivered by the USC Norris Comprehensive Cancer Center. The strategic undertaking is anchored by four key pillars. These include clinical testing, which can enable detailed molecular and genetic profiling at the patient level; clinical trials matching, which automatically matches eligible patients with novel targeted therapies; clinical care gap pathways, which uses AI-driven insights to promote evidence-based patient care; and research collaboration and co-development, aimed at moving academic discoveries into real-world diagnostics and treatments. Together, these elements have the potential to create an integrated ecosystem that connects patient care and research. This collaboration will start with a focus on precision oncology, with the intension of creating a proven model for integrating care and research, that can then be extended over time to other specialties, including cardiology, neurology and radiology.

Statement Highlights: Personalized guidance about the appropriate amount and type of physical activity for children with heart conditions relies on diagnosis, individual risk profile and personal and family goals. Ongoing follow-up and shared decision-making among patients, families and their health care team are critical.

Scientific research teams from Brigham and Women’s Hospital in Boston, Cincinnati Children’s Hospital Center and the University of Pittsburgh will lead a new $15 million initiative dedicated to better understanding how to diagnose and treat heart valve disease.

How fit you are in midlife may help determine not just how long you live, but how many of those years are spent in good health, according to a new study published today in the JACC, the flagship journal of the American College of Cardiology.