Common cold sore virus may reprogram the brain’s immune defenses
Peer-Reviewed Publication
In honor of Alzheimer's Awareness Month, we’re exploring the science and stories surrounding Alzheimer’s disease.
Updates every hour. Last Updated: 20-Oct-2026 03:16 ET (20-Oct-2026 07:16 GMT/UTC)
A very common virus may do more than cause cold sores. Researchers at the University of Colorado Anschutz have discovered how herpes simplex virus type 1 (HSV-1), the virus that causes cold sores, can fundamentally change how the brain’s immune cells respond to infection, revealing a potentially important connection between viral infection, chronic inflammation and Alzheimer’s Disease.
Urban residents with more greenery within 100 metres of their homes have a lower risk of developing dementia over time. This is the finding of a new study from Stockholm University and Karolinska Institute, which followed nearly 3,000 older adults for 16 years. Published in the journal Alzheimer’s & Dementia, the study highlights the importance of greenspace in the immediate surroundings of the home for sustainable urban planning that supports brain health.
Alzheimer’s disease may not be a single, uniform condition, but a complex disorder shaped by different combinations of cognitive symptoms, brain changes, biology, genetics, and risk factors. Researchers propose using advanced computational modelling to bring these different layers together and build a more complete profile of each patient. The approach could eventually support more personalized diagnosis, better patient stratification, and treatments tailored to the processes driving disease in each individual.
A Michigan Medicine study found major disparities in access to new Alzheimer’s drugs, with Black and Hispanic patients less likely to receive treatment, though adherence was similar once therapy began.
Upstate Medical University has received $1.5 million in state funding as part of the SUNY Brain Institute, a $10 million collaborative effort to strengthen neuroscience research across SUNY campuses. The investment will expand New York’s capacity to study Alzheimer’s disease, Parkinson’s disease, stroke, and other age-related brain disorders by connecting researchers, specialized equipment, and advanced research infrastructure. At Upstate, the funding will support development of patient-derived stem cell and brain organoid models that more closely replicate human disease, helping researchers better understand disease progression and evaluate potential treatments. The initiative is designed to accelerate discovery, foster collaboration across institutions, and address the growing burden of neurological diseases on New Yorkers as the population ages.