New study reveals how tiny but powerful gatekeepers guard the nucleus
Peer-Reviewed Publication
In honor of Alzheimer's Awareness Month, we’re exploring the science and stories surrounding Alzheimer’s disease.
Updates every hour. Last Updated: 27-Oct-2025 21:11 ET (28-Oct-2025 01:11 GMT/UTC)
Nuclear pore complexes (NPCs) control the rapid flow of materials between a cell’s nucleus and its cytoplasm, but its innerworkings have long remained a mystery. Now researchers have unveiled the most complete picture yet of how NPCs make split-second decisions about which molecules to let pass through. The model opens new avenues for medical and biotech innovation, including therapeutics for NPC-associated genetic diseases such as Alzheimer’s and ALS.
Dr. Brett Finlay is a leading expert in how microbes affect health for better and for worse. He teamed up with his daughter, gerontologist Jessica Finlay, to publish their new book The Microbiome Master Key, which explores the unexpected ways in which microbes influence areas ranging from cognition and mood to immunity and susceptibility to disease. In this Q&A, the authors dissect the latest microbiome research, dispel common myths and provide simple, science-backed tips on how to leverage your microbiome to promote healthy living and aging.