Preventing onset and development of heart failure with preserved ejection fraction
Peer-Reviewed Publication
In recognition of Heart Health Month, we’re spotlighting the importance of cardiovascular wellness. From risk factors and prevention to innovative treatments, we’re exploring the science and stories shaping heart health today.
Updates every hour. Last Updated: 10-Sep-2025 10:11 ET (10-Sep-2025 14:11 GMT/UTC)
An international team of researchers has discovered a natural mechanism that protects the heart from heart failure with preserved ejection fraction (HFpEF), a serious condition in need of effective treatment. The team reports that when the cardioprotective mechanism fails, it promotes the development of HFpEF. Importantly, restoring the mechanism prevents the progression of the condition. The findings provide a promising therapeutic target to prevent and treat this life-threatening disease.
People with a certain heart valve abnormality are at increased risk of severe heart rhythm disorders, even after successful valve surgery. This is according to a new study from Karolinska Institutet and Karolinska University Hospital in Sweden published in the European Heart Journal. The condition is more common in women and younger patients with valve disorder and can, in the worst case, lead to sudden cardiac arrest.
Major reallocation of healthcare services during the COVID-19 pandemic meant that elective surgery in children with congenital heart disease (CHD) was significantly reduced, so that those needing urgent, lifesaving and emergency surgery could be treated. However, this prioritisation of the most severely ill children did not increase overall post-operative complications rates or death, a study led by the University of Bristol has shown.
The TCT® 2025 Career Achievement Award will be presented to Stephan Windecker, MD, during Transcatheter Cardiovascular Therapeutics® (TCT®), the annual scientific symposium of the Cardiovascular Research Foundation® (CRF®). TCT® will take place October 25-28, 2025, in San Francisco, California at the Moscone Center. The award is given each year to an outstanding individual who has made extraordinary contributions to the field of interventional cardiology and has transformed cardiovascular care through clinical excellence, pioneering research, and mentorship of the next generation of physicians and researchers.
The persistent higher rate of alcohol deaths in England since the pandemic in 2020 is an “acute crisis” requiring urgent action from government, according to a new study led by researchers at UCL and the University of Sheffield.