In a world-first, a team of researchers at the National Institutes of Health (NIH) and Emory School of Medicine, Atlanta, has successfully performed a coronary artery bypass — a normally open-heart surgery — without cutting the chest wall. The team employed a novel intervention to prevent the blockage of a vital coronary artery, which is a very rare but often lethal complication following a heart-valve replacement. The results suggest that, in the future, a less traumatic alternative to open-heart surgery could become widely available for those at risk of coronary artery obstruction.

Women with severe coronary heart disease causing narrowing or blockages in the arteries may derive greater long-term benefits from coronary artery bypass grafting compared with percutaneous coronary intervention, also known as stenting, according to a large study by Weill Cornell Medicine investigators.

Patients who start their blood pressure treatment with ARB drugs continue with the same medicine to a greater extent than patients who start out with other drugs. Choosing the right drug from the outset can therefore improve both health and quality of life – as well as bringing down healthcare costs. This is shown in a new study based on data from 340,000 patients.

The American College of Cardiology (ACC) and the American Heart Association, along with several other leading medical associations, have issued a new guideline for managing congenital heart disease in adults. The guideline was jointly published today in JACC, the flagship journal of the American College of Cardiology, and Circulation, the flagship journal of the American Heart Association. 

Patients with depression are at higher risk of cardiovascular disease, and a new study suggests that stress may help explain why. Research from Mass General Brigham suggests that this increased risk is driven by stress-related brain activity, nervous system dysregulation, and chronic inflammation. They also found that patients with both depression and anxiety were at even higher risk of cardiovascular disease than those diagnosed with just one condition. The findings, published in Circulation: Cardiovascular Imaging, suggest that stress reduction and related therapeutic targets hold potential for cardiovascular disease prevention.

The largest-ever study testing the effectiveness of an evidence-based approach to increasing physical activity using smartphone fitness trackers gamification to reduce the risk of cardiovascular disease will launch at the Perelman School of Medicine at the University of Pennsylvania and Ascension, one of the nation’s leading non-profit health systems , thanks to a $25 million award. The six-year study, funded by the Patient-Centered Outcomes Research Institute (PCORI), will build on the highly successful BE ACTIVE trial, published in 2024, which demonstrated sustained increases in daily step counts using a behavioral economics based approach to gamification to enhance ongoing engagement, where participants were awarded points for meeting daily step goals and progress through levels based on accumulated points.

Doctors may soon be able to diagnose an elusive form of heart disease, coronary microvascular dysfunction, within seconds by using an AI model developed at University of Michigan, according to a recent study.The prediction tool significantly outperformed earlier AI models in nearly every diagnostic task and has potential to be a cost-effective diagnostic tool at non-specialty hospitals. 

Effective prevention and treatment of gum disease, also called periodontal disease, could potentially decrease the burden of cardiovascular disease, according to a new scientific statement published today in the American Heart Association’s flagship journal Circulation.