Breakthrough Mount Sinai study is the first to link this symptom to the novel synthetic drug in opioid overdose; findings can help doctors save lives during emergencies

Mechanical cues are key regulators of cardiac development, yet their role in organoid maturation remains underexplored. In a new study, researchers introduce a magnetic torque stimulation (MTS) system that delivers precisely controlled rotational forces to stem cell-derived cardiac organoids via surface-bound magnetic particles. Application of MTS significantly improves cardiac organoid maturation and vascularization by activating mechanotransduction pathways, offering a powerful platform for studying cardiac diseases and testing drug safety.

Persistent somatic symptoms are a common feature in many psychiatric disorders. Moderate-to-severe cases often necessitate treatment in specialised inpatient psychiatric settings. This study evaluated the efficacy, safety and acceptability of resonant breathing (personalised slow breathing to maximise heart rate variability (HRV)) as adjunctive treatment for hospitalised patients with psychiatric disorders presenting with persistent somatic symptoms on admission, when patients typically present with high symptom severity.