A study conducted by researchers from the University of Plymouth and Plymouth Marine Laboratory, who have spent more than a decade examining the impact of artificial light at night (ALAN) on the world’s coasts and oceans, has shown that more than one-fifth of the global ocean – an area spanning more than 75million sq km – has been the subject of ocean darkening over the past two decades. Ocean darkening occurs when changes in the optical properties of the ocean reduce the depth of its photic zones, home to 90% of all marine life and places where sunlight and moonlight drive ecological interactions.

How can we fabricate an artificial brain that mimics the natural brain, from structure to function?

In response to this question, researchers from Xi’an Jiaotong University published a review paper outlining the primary requirements and challenges in biomanufacturing brain-like tissue, summarizing the existing technologies, strategies, and characteristics, and reviewing the cutting-edge developments in biomanufacturing central neural repair prosthetics, brain development models, brain disease models, and brain-inspired biocomputing models.

This review helps readers systematically understand the challenges, current progress, and future directions of brain-like living tissue manufacturing.