State gun laws and firearm-related homicides and suicides
Peer-Reviewed Publication
This month, we're turning our attention to National Suicide Prevention Awareness Month, an important time dedicated to raising awareness, breaking stigma, and exploring the science behind mental health and suicide prevention.
Updates every hour. Last Updated: 12-Dec-2025 15:11 ET (12-Dec-2025 20:11 GMT/UTC)
A groundbreaking new review comprehensively synthesizes the latest developments in next-generation chimeric antigen receptor T cell (CAR-T) therapies, highlighting key preclinical and clinical breakthroughs in the treatment of lymphoma. The article examines barriers to CAR-T efficacy and provides an in-depth analysis of innovative strategies, including multi-specific CAR, T cells redirected for universal cytokine-mediated killing (TRUCKs), switch receptor CAR, safety switch/suicide system, and in vivo CAR-T cells. With a special focus on the role of epigenetics and metabolism in CAR-T cell exhaustion, the review offers valuable insights and future directions for advancing CAR-T immunotherapy.
New research found that youth who become increasingly addicted to social media, mobile phones or video games are at greater risk of suicidal thoughts, suicide attempts and emotional or behavioral issues. The study, published June 18 in JAMA, was led by researchers at Weill Cornell Medicine, Columbia University and University of California, Berkeley.