Interactions among viruses can help them succeed inside their hosts or impart vulnerabilities that make them easier to treat. Scientists are learning the ways viruses mingle inside the cells they infect, as well as the consequences of their socializing. Although it is debatable whether viruses are living things, they do compete, cooperate and share genome materials that can sometimes alter their responses to antiviral drugs, result in new variants or play a role in virus evolution. A paper today in Nature Ecology & Evolution by UW Medicine scientists looks at the evolution of poliovirus resistance to a promising experimental antiviral drug, pocapavir. While it seemed counterintuitive, the researchers demonstrated that lowering the potency of pocapavir could improve the situation by enhancing the survival of enough susceptible viruses to continue sensitizing the resistant ones.

The discovery holds the potential to inspire innovations in biotechnology, from the development of new “smart” materials to nanoscale drug delivery systems.

A major academic medical center achieved the effect of adding 63 beds, giving more patients access to advanced care, by creating a data-driven command center for bed use and procedures to find ways to safely reduce length of stay and more.

When people are feeling happy, they’re more likely to see other people as happy. If they’re feeling down, they tend to view other people as sad. But when dealing with dogs, this well-established psychological effect ceases to work as expected. In one experiment, the effect actually worked in reverse: people prompted to feel upbeat tended to rate dogs as being sadder. Those nudged into a negative mood deemed dogs to be happier, behavioral scientists at Arizona State University report.

Wastewater from washing machines is considered a major source of microplastics – tiny plastic particles that are suspected of harming human and animal health. Researchers at the University of Bonn now have developed a filter to curb this problem. Their filter was inspired by the gill arch system in fish. In initial tests, the now patent-pending filter was able to remove over 99 percent of plastic fibers from washing machine wastewater. The results now have been published in the journal npj Emerging Contaminants.