Social lives of viruses affect antiviral resistance
Peer-Reviewed Publication
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Updates every hour. Last Updated: 15-May-2026 12:15 ET (15-May-2026 16:15 GMT/UTC)
Interactions among viruses can help them succeed inside their hosts or impart vulnerabilities that make them easier to treat. Scientists are learning the ways viruses mingle inside the cells they infect, as well as the consequences of their socializing. Although it is debatable whether viruses are living things, they do compete, cooperate and share genome materials that can sometimes alter their responses to antiviral drugs, result in new variants or play a role in virus evolution. A paper today in Nature Ecology & Evolution by UW Medicine scientists looks at the evolution of poliovirus resistance to a promising experimental antiviral drug, pocapavir. While it seemed counterintuitive, the researchers demonstrated that lowering the potency of pocapavir could improve the situation by enhancing the survival of enough susceptible viruses to continue sensitizing the resistant ones.
The discovery holds the potential to inspire innovations in biotechnology, from the development of new “smart” materials to nanoscale drug delivery systems.
WASHINGTON, D.C. — A U.S. Naval Research Laboratory’s (NRL) space robotics team received the Best Paper Award in Orbital Robotics at the 2025 International Conference on Space Robotics (iSpaRo) in Sendai, Japan, on Dec. 3. The recognition spotlights NRL’s leadership in autonomous space systems and artificial intelligence–enabled operations.