New research from Edith Cowan University (ECU) has found that higher sodium intake may negatively affect episodic memory, the type of memory used to recall personal experiences and specific events from one’s past such as where you parked your car or your first day of school.  

A study measuring daily rest-activity rhythms in older adults with no cognitive impairment found that weaker, more fragmented daily rhythms were associated with smaller memory-related brain regions and, in subsequent follow-ups, faster brain atrophy.  

A new study by investigators at Mass General Brigham has found that a blood test of plasma phosphorylated tau 217 (pTau217), an Alzheimer's disease biomarker, can predict the progression of amyloid PET scan changes and cognitive decline in cognitively healthy older adults. The findings may help push back the clock to enable simpler, earlier disease prediction and indicate who may be at risk for cognitive decline.

Scientists at the Buck Institute for Research on Aging, along with collaborators at UC San Francisco, have discovered that APOE4, the most common genetic risk factor for Alzheimer’s disease, causes bone quality deficits specifically in female mice, through a mechanism that is invisible to standard imaging and can emerge as early as midlife.