Blood vessels and immune cells drive risk for Alzheimer’s and stroke
Peer-Reviewed Publication
In honor of Alzheimer's Awareness Month, we’re exploring the science and stories surrounding Alzheimer’s disease.
Updates every hour. Last Updated: 2-Nov-2025 02:11 ET (2-Nov-2025 07:11 GMT/UTC)
The brain’s health depends on more than just its neurons. A complex network of blood vessels and immune cells acts as the brain’s dedicated guardians—controlling what enters, cleaning up waste, and protecting it from threats by forming the blood-brain barrier. A new study from Gladstone Institutes reveals that many genetic risk factors for neurological diseases like Alzheimer’s and stroke exert their effects within these very guardian cells.
The Davos Alzheimer’s Collaborative (DAC),presents significant new research and implementation outcomes at the 2025 Alzheimer’s Association International Conference (AAIC) in Toronto, Canada. These include data from multi-site healthcare system implementation projects and the expansion of DAC’s research footprint across five continents.
Mathematics may not be the first thing people associate with Alzheimer’s disease research. But for Pedro Maia, an assistant professor of mathematics and data science at The University of Texas at Arlington, analyzing how different parts of the brain interact like a network is revealing new insights into one of the world’s most devastating brain disorders.
TripletDGC, an open-source GitHub toolkit, leverages single-cell RNA-seq to map nearly 10,000 disease-associated genes to their most impacted cell types—creating over 54,000 gene-disease-cell links to accelerate precision medicine and targeted drug discovery.