A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction and memory loss in Alzheimer’s disease. A tool, developed in the Tracy lab, enables researchers to track changes in the synaptic proteome, correlating changes to synaptic dysregulation and synapse loss over time. The results and the tool, which is available to all researchers, are now online at Molecular Neurodegeneration.

According to Hui Yang, Gary and Sheila Bello Chair in Industrial and Manufacturing Engineering at Penn State, and Kevin Mekulu, an industrial engineering and operations research doctoral candidate, artificial intelligence (AI) could be used to better understand and detect neurodegenerative diseases like dementia and Alzheimer's. In a Q&A, Yang and Mekulu shared how AI-powered screening methods could contribute to cognitive care, helping clinicians intervene sooner and improve patient outcomes. 

Almost half of all dementia cases can be attributed to risk factors that we potentially can influence ourselves, such as smoking and high blood pressure. A new study from Lund University shows which risk factors are associated with two of our most common causes of dementia – Alzheimer's disease and vascular dementia.

Alzheimer Europe has today launched the “The Prevalence of Dementia in Europe 2025” report, which provides updated prevalence figures for the number of people living with dementia both for Europe as a whole, as well as the countries within. The report builds upon Alzheimer Europe’s previous work in the “Dementia in Europe Yearbook 2019”.