Mayo Clinic researchers identify a new stem cell patch to gently heal damaged hearts
Peer-Reviewed Publication
In recognition of Heart Health Month, we’re spotlighting the importance of cardiovascular wellness. From risk factors and prevention to innovative treatments, we’re exploring the science and stories shaping heart health today.
Updates every hour. Last Updated: 13-Dec-2025 16:12 ET (13-Dec-2025 21:12 GMT/UTC)
Doxorubicin (DOX) is widely used to treat cancer but can cause severe heart damage. In a recent study, researchers from China identified glutathione S-transferase P1 (GSTP1) as a crucial protective factor against DOX-induced cardiomyopathy. They revealed that GSTP1 suppresses acyl-CoA synthetase long-chain family member 4 (ACSL4)-dependent ferroptosis through the JNK signaling pathway, reducing oxidative stress and highlighting GSTP1 as a promising therapeutic target for preventing DOX-related heart injury.
A new study shows children and young people faced long-lasting and higher risks of rare heart and inflammatory complications after COVID-19 infection, compared to before or without an infection. Meanwhile COVID-19 vaccination was only linked to a short-term higher risk of myocarditis and pericarditis.
Adults with elevated levels of three biomarkers for heart disease—lipoprotein a (also called Lp(a)), remnant cholesterol and high-sensitivity C-reactive protein (hsCRP)—had nearly triple the risk of heart attack compared to those without elevated levels.