Owning a smartphone before age 13 is associated with poorer mind health and wellbeing in early adulthood, according to a global study of more than 100,000 young people.

About The Study: In this cross-sectional study, stronger gun laws correlated with decreased overall firearm mortality, with the strongest correlations for decreased suicides. For firearm suicide, this analyses lend support to policies that regulate firearm sales, transfers, and permitting laws. While some gun law categories were correlated with decreased firearm homicide, sociodemographic factors, such as unemployment, poverty, and insurance status, correlated with larger changes, suggesting policies that address root causes of violence through economic mobility and access to robust social, health, and educational services may be associated with a greater reduction in homicides. 

Two studies led by researchers at the NYU School of Global Public Health find both geographic differences and personal factors that shape where people might seek help during mental health crises.

The latest issues of three American Psychiatric Association journals (The American Journal of Psychiatry, Psychiatric Services, American Journal of Psychotherapy, and Psychiatric Research and Clinical Practice) are now available online. 

A groundbreaking new review comprehensively synthesizes the latest developments in next-generation chimeric antigen receptor T cell (CAR-T) therapies, highlighting key preclinical and clinical breakthroughs in the treatment of lymphoma. The article examines barriers to CAR-T efficacy and provides an in-depth analysis of innovative strategies, including multi-specific CAR, T cells redirected for universal cytokine-mediated killing (TRUCKs), switch receptor CAR, safety switch/suicide system, and in vivo CAR-T cells. With a special focus on the role of epigenetics and metabolism in CAR-T cell exhaustion, the review offers valuable insights and future directions for advancing CAR-T immunotherapy.