Changes in gut microbiota influence which patients get AIG-related neuroendocrine tumors
Peer-Reviewed Publication
Updates every hour. Last Updated: 6-Nov-2025 05:11 ET (6-Nov-2025 10:11 GMT/UTC)
Researchers investigated how autoimmune gastritis alters the gastric microbiota and disrupts metabolism, shedding light on mechanisms that contribute to the development of neuroendocrine tumors.
2025 Nobel Laureate in Physiology or Medicine Professor Shimon Sakaguchi at the Immunology Frontier Research Center, The University of Osaka delivered his message on 6 October 2025.2025 Nobel Laureate in Physiology or Medicine Professor Shimon Sakaguchi at the Immunology Frontier Research Center, The University of Osaka delivered his message on 6 October 2025.
Work engagement is a persistent, positive state of mind that enhances productivity, creativity, and well-being. However, few practical methods exist to foster it. Addressing this gap, researchers from Japan developed WEDiary, a smartphone app that encourages daily positive reflection on work achievements. In a randomized controlled trial involving 600 Japanese workers, the app significantly improved work engagement levels in only 2 weeks, with effects lasting 3 weeks beyond the intervention.
Entrepreneurship studies often focus on firm growth-related topics. The factors affecting the high-growth (HG) in high-growth firms (HGFs) are not well established. While some studies suggest that proactive strategizing precedes the HG period, others consider that the near-random structure of the firm’s growth is better to delay growth-related investments. This study focuses on the “timing” of setting up new hierarchical layers and the consequences if it happens before or after the growth event.
Cells all require the transport of materials to maintain their function. In nerve cells, a tiny motor made of protein called KIF1A is responsible for that. Mutations in this protein can lead to neurological disorders, including difficulties in walking, intellectual impairment and nerve degradation. It’s known that mutations in KIF1A also result in a weakened motor performance, but this has been difficult to measure so far. Researchers including those from the University of Tokyo and the National Institute of Information and Communications Technology (NICT) in Japan have measured changes in the force of KIF1A using a nanospring, a tiny, coiled structure, made of DNA which could lead to improved diagnosis of diseases related to the protein’s mutations.