Pioneering green chemistry: Light and air combine to build key molecules for future medicines
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Dec-2025 09:11 ET (26-Dec-2025 14:11 GMT/UTC)
The University of Osaka researchers developed a world-first sustainable method for synthesizing pharmaceutical-grade NOBIN. By cooperatively utilizing a vanadium catalyst and energy-efficient LED light, the process eliminates byproducts, reduces waste, and allows for ideal raw material ratios, paving the way for greener and more efficient chiral molecule production.
The confinement performance of magnetically confined fusion plasmas is affected by turbulence at various scales. Understanding not only the effects of turbulence at each scale but also the interactions between these turbulent eddies is a critical research challenge for realizing efficient fusion power reactors.
A research group led by Professor Tokihiko Tokuzawa and Project Professor Katsumi Ida of the National Institute for Fusion Science, graduate student Tatsuhiro Nasu of the Graduate University for Advanced Studies, and Professor Shigeru Inagaki of Kyoto University has developed a precise measurement system capable of simultaneously observing turbulence at different scales at the same location within the high-temperature plasma of the Large Helical Device (LHD). They discovered that large turbulent eddies deform smaller turbulent eddies, thereby suppressing their growth. Conventional models of plasma confinement did not account for this cross-scale interaction mechanism. This finding provides important insights for predicting the plasma confinement performance in future fusion power reactors.
A paper detailing these research findings was published in the journal Communications Physics on October 6th.
The ability of CD8+ T cells, a type of immune cell, to rapidly proliferate inside tumors is key to the success of cancer immunotherapy. In a new study, scientists from Tokyo University of Science, Japan, have identified a set of ‘signature’ genes that can determine whether these immune cells will multiply or stall within the tumor. Their findings provide a powerful pan-immunotherapy biomarker for treatment monitoring and pave the way for next-generation immunodynamic therapies.
High costs have long held back hydrogen production from water, with electrolyzers priced at $2,000–$2,600 per kilowatt in 2024. Now, researchers from Japan have found that modifying platinum cathodes with naturally occurring purine bases can boost the hydrogen evolution reaction (HER) activity, the key step where water is split into hydrogen, up to four times. This approach can significantly reduce platinum requirements, bringing affordable, large-scale hydrogen production closer to reality.
Traditional geotechnical investigations provide data only at discrete borehole locations, leaving vast areas uncharacterized. This spatial gap often leads to unforeseen ground conditions during construction, causing costly delays, design modifications, and occasionally catastrophic failures. Now, a novel integrated geophysical-machine learning approach, using k-means clustering technique, by a team of researchers from Shibaura Institute of Technology provides continuous subsurface characterization, enabling evidence-based decision-making throughout project lifecycles.
Miniaturized electronics and intricate objects require a certain finesse. Here, researchers look into the development of a machine capable of these fine movements, as well as identifying and categorizing the objects using machine learning.
A Japanese research team has mathematically revealed why crack tips sharpen during rapid fracture in rubber. The study demonstrates that this phenomenon is caused solely by the material’s viscoelasticity, not by previously assumed nonlinear effects. They also validated the long-standing viscoelastic trumpet theory, proposed by Nobel Laureate Pierre-Gilles de Gennes, using fundamental equations of continuum mechanics. This work establishes a theoretical foundation for fracture control and durability improvement of a wide range of polymer materials from tires to medical devices.
Kyoto, Japan -- Life-history variation is fundamental to the long-term persistence of populations and species because it ensures their ability to adapt to changing environments. Many important studies have focused on life-history variation between habitats, but the variation maintained within a habitat has often been overlooked.
Unravelling this puzzle at the landscape level is critical for understanding the spatial scales at which adaption and population persistence operate in nature. This motivated a team of researchers at Kyoto University to investigate life-history variation in masu salmon.
"We wanted to understand how the variation in life-history is partitioned within and among habitats across heterogeneous landscapes," says first author Takeya Shida.