Scientists reveal how a key inflammatory molecule triggers esophageal muscle contraction
Peer-Reviewed Publication
Updates every hour. Last Updated: 13-Aug-2025 14:11 ET (13-Aug-2025 18:11 GMT/UTC)
A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has uncovered important details about how platelet-activating factor (PAF)—a powerful molecule involved in inflammation and allergic reactions—triggers contractions in the smooth muscles of the esophagus. Their findings could pave the way for new treatments targeting gastrointestinal symptoms associated with allergies, asthma, and anaphylaxis.
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