Uncovering hyper-maturity and accelerated aging in the hippocampus
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Dec-2025 07:12 ET (26-Dec-2025 12:12 GMT/UTC)
Researchers at Fujita Health University and collaborators identified "hyper-maturity" in the hippocampus, excessive cellular aging, as a shared abnormality in mouse models of anxiety and other psychiatric disorders. By screening public transcriptomics datasets, they found hyper-mature signatures linked to increased anxiety. This study, published in Neuropsychopharmacology, extends beyond the authors’ previous findings on immature brain phenotypes, suggesting that both under- and over-maturation can disrupt emotional regulation, offering a new paradigm for psychiatric and aging research.
Carbynes, or long linear carbon chains (LLCCs), have received significant attention in recent years due to their predicted exceptional properties. However, experimentally, their properties have been hard to probe due to their low stability. To improve stability, it is necessary to encapsulate LLCCs in small diameter carbon nanotubes (CNTs). Now, researchers have developed a new method to synthesize small diameter single-walled carbon nanowires (SWCNWs), featuring high-density LLCCs encapsulated in single-walled CNTs.
Researchers at The University of Osaka and The University of Tokyo developed a photoactivatable alkyne tag that enables stable, selective visualization of biomolecules inside living cells. The technology would contribute to reveal previously unseen molecular communication, paving the way for advances in cell biology and drug discovery.
The henna tree is commonly used for making henna dye. Now, a new study suggests that the same pigments that change your skin or hair that distinctive orange-red color could be used for another purpose: treating liver disease.
Researchers at AIMR demonstrated that the quantum metric, a hidden property of electronic states, can be measured and controlled under ambient conditions. Using a Mn3Sn/Pt heterostructure with engineered interfacial spin textures, they revealed a robust second-order Hall effect, opening new pathways for topological electronics and quantum-geometry–based devices.