News from Japan
Updates every hour. Last Updated: 6-May-2025 04:09 ET (6-May-2025 08:09 GMT/UTC)
Clarifying the mechanism of coupled plasma fluctuations using simulations
National Institutes of Natural SciencesPeer-Reviewed Publication
- Journal
- Scientific Reports
- Funder
- MEXT, JSPS KAKENHI, JSPS Core-to-Core Program, A. Advanced Research Networks, the National Institutes of Natural Sciences program of Promoting Research by Networking among Institutions, the European Union via the Euratom Research and Training Programme, the NIFS Collaboration Research program
Dolphins use a 'fat taste' system to get their mother’s milk
Hokkaido UniversityPeer-Reviewed Publication
Juvenile dolphins were found to have specialized receptors for fatty acids on their tongues, offering new insights into their growth and feeding habits.
- Journal
- Marine Mammal Science
- Funder
- Japan Society for the Promotion of Science, Japan Science Society, Kyoto University, Hokkaido University
Can DNA-nanoparticle motors get up to speed with motor proteins?
National Institutes of Natural SciencesPeer-Reviewed Publication
DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion by enzymatic RNA degradation. Essentially, chemical energy is converted into mechanical motion by biasing the Brownian motion. The DNA-nanoparticle motor uses the "burnt-bridge" Brownian ratchet mechanism. In this type of movement, the motor is being propelled by the degradation (or "burning") of the bonds (or "bridges") it crosses along the substrate, essentially biasing its motion forward.
These nano-sized motors are highly programmable and can be designed for use in molecular computation, diagnostics, and transport. Despite their genius, DNA-nanoparticle motors don't have the speed of their biological counterparts, the motor protein, which is where the issue lies. This is where researchers come in to analyze, optimize, and rebuild a faster artificial motor using single-particle tracking experiment and geometry-based kinetic simulation.
- Journal
- Nature Communications
- Funder
- JSPS KAKENHI, Grant-in-Aid for Transformative Research Areas (A) (Publicly Offered Research), "Molecular Cybernetics", JSPS KAKENHI, Grant-in-Aid for Transformative Research Areas (A) (Publicly Offered Research), "Materials Science of Mesohierarchy", JSPS KAKENHI, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), "Molecular Engine", JSPS KAKENHI, Grant-in-Aid for Early-Career Scientists, JST ACT-X, "Life and Information", Tsugawa Foundation Research Grant for FY2023
Novel molecular insights into bone remodeling
Institute of Science TokyoPeer-Reviewed Publication
The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the development of innovative therapeutic strategies to counter osteoporosis. Their research findings reveal the intrinsic role of Fam102a in the nuclear trafficking of key transcription factors-regulatory proteins involved in the complex bone remodeling process
- Journal
- Nature Communications
- Funder
- Japan Agency for Medical Research and Development, Japan Society for the Promotion of Science, Takeda Science Foundation, Astellas Foundation for Research on Metabolic Disorders, Daiichi Sankyo Foundation, Secom Science and Technology Foundation
New ceramic catalyst uses sodium and boron to drive sustainable industrial reactions
Nagoya Institute of TechnologyPeer-Reviewed Publication
Transition metals have long been used as catalysts to activate small molecules and turn them into valuable products. However, as these metals can be expensive and less abundant, scientists are increasingly looking at more common elements as alternatives. In a recent study, researchers used a concept called “frustrated Lewis pairs” to develop a transition metal-free catalyst for activating hydrogen. This breakthrough could lead to more sustainable, cost-effective, and efficient chemical processes.
- Journal
- Angewandte Chemie International Edition
- Funder
- Japan Society for the Promotion of Science, Centre National de la Recherche Scientifique
Elucidation of the mechanism behind frontotemporal lobar degeneration
Toho UniversityPeer-Reviewed Publication
- Journal
- Disease Models & Mechanisms
- Funder
- Japan Society for the Promotion of Science, Tokyo Medical and Dental University, Toho University
Manipulating intracellular signal transduction using optogenetic technology
Toho UniversityPeer-Reviewed Publication
- Journal
- Development
- Funder
- Toho University, Japan Society for the Promotion of Science
CB2 receptor agonist improves memory performance in Alzheimer's disease mouse models
Nagoya UniversityPeer-Reviewed Publication
- Journal
- Cell Death and Disease