Consumption of eggs is associated with a lower risk of being diagnosed with Alzheimer's Disease for those 65 years and older, according to researchers at Loma Linda University Health

 

Study shows that lead iodide can support phonon-polaritons, allowing radiation to be confined on a nanoscale and enabling new data transmission devices.

Alzheimer’s disease develops over many years before symptoms appear, with underlying processes such as amyloid plaque buildup, tau pathology, neuroinflammation, and neuronal loss. A key turning point occurs when amyloid-β accumulation triggers tau phosphorylation, leading to neuronal damage and eventual cognitive decline. Historically, this early stage has been difficult to study in living patients. In this Perspective, De Strooper and Zetterberg highlight a newly developed blood-based biomarker, phosphorylated tau 217 (pTau217), which allows detection of early pathological changes associated with Alzheimer’s disease without invasive procedures. According to the authors, the identification and validation of pTau217 enables highly specific, in vivo detection of the transition from amyloid accumulation to tau-driven neuronal injury, making it possible to study and identify this previously inaccessible early disease stage. “The next challenge will be to develop therapies that directly interrupt the induction and propagation of tau pathology captured by plasma pTau217,” write the authors. “Ultimately, however, the impact of this diagnostic progress will depend on whether these biomarkers can be deployed in ways that meaningfully improve patient outcomes once effective preventive therapies become available.”