EurekAlert! In the Spotlight - Alzheimer's Awareness Month

Welcome to In the Spotlight, where each month we shine a light on something exciting, timely, or simply fascinating from the world of science.

In honor of Alzheimer's Awareness Month, we’re exploring the science and stories surrounding Alzheimer’s disease.

Latest News Releases

Updates every hour. Last Updated: 10-Sep-2025 05:11 ET (10-Sep-2025 09:11 GMT/UTC)

24-Jul-2025

New approach maps nearly 10,000 disease genes to 93 complex diseases, creating 54,240 gene-disease-cell links for precision medicine

TripletDGC, an open-source GitHub toolkit, leverages single-cell RNA-seq to map nearly 10,000 disease-associated genes to their most impacted cell types—creating over 54,000 gene-disease-cell links to accelerate precision medicine and targeted drug discovery.

Journal: Frontiers of Computer Science

23-Jul-2025

New study validates insulin nasal spray to deliver Alzheimer’s drug directly to the brain

Atrium Health Wake Forest Baptist
Peer-Reviewed Publication

A groundbreaking brain imaging study from Wake Forest University School of Medicine confirms a vital step toward new Alzheimer’s disease treatments: Intranasal insulin, delivered via a simple nasal spray, safely and effectively reaches key memory regions of the brain in older adults. The study also revealed that people with early cognitive decline absorb it differently.

Journal: Alzheimer s & Dementia Translational Research & Clinical Interventions

22-Jul-2025

Mount Sinai researcher decodes brain and body communication that drives aging and depression

Genomic Press
Reports and Proceedings

Dr. Hamilton Se-Hwee Oh at Mount Sinai in New York pioneers research linking differential organ aging to depression and Alzheimer's disease. His Stanford PhD work yielded breakthrough Nature publications showing organs age at different rates. Now investigating how psychological stress accelerates aging and how peripheral signals rewire brain circuits affecting mood and cognition.

Journal: Brain Medicine

21-Jul-2025

Research Spotlight: Finding new insights into neurodegeneration from artificial intelligence and brain imaging

Mass General Brigham
Peer-Reviewed Publication

Matthew Leming, PhD, and Hyungsoon Im, PhD of the Center for Systems Biology at Massachusetts General Hospital, are the co-corresponding authors of a paper published in Alzheimer’s & Dementia, “Differential dementia detection from multimodal brain images in a real-world dataset.”

Journal: Alzheimer s & Dementia
Funder: NIH/National Institutes of Health, Massachusetts General Hospital, NIH Office of the Director

21-Jul-2025

Do these two cancer drugs have what it takes to beat Alzheimer’s?

University of California - San Francisco
Peer-Reviewed Publication

Scientists at UC San Francisco and Gladstone Institutes have identified cancer drugs that promise to reverse the changes that occur in the brain during Alzheimer’s, potentially slowing or even reversing its symptoms.

Journal: Cell
Funder: NIH/National Institute on Aging, NIH/National Institute on Aging, NIH/National Institute on Aging, NIH/National Institute on Aging, NIH/National Institute on Aging, U.S. National Science Foundation, Dolby Family Ventures

21-Jul-2025

Frontiers supports Alzheimer's research with expert-led interview series focused on open data and drug discovery

Frontiers

Frontiers today announces the launch of a new interview series ‘Empowering proteomics and transcriptomics in Alzheimer’s drug discovery’. The series is hosted by Dr Ornit Chiba-Falek, Specialty Chief Editor of Frontiers in Molecular Medicine and Division Chief of Translational Brain Sciences in the Department of Neurology at Duke University, and Dr Ara Khachaturian, Executive Vice President of the Campaign to Prevent Alzheimer’s Disease.