Ecosystems are characterized by interconnected structure and functions. A study published July 8^th in the open-access journal PLOS Biology by Casey Benkwitt at Lancaster University, United Kingdom and colleagues suggests that restoring seabird populations via eradication of rats may help coral reefs by restoring nutrient connectivity in disrupted food chains.

A fundamental discovery by University of Missouri scientists could help solve one of the most frustrating challenges in treating lung cancer: Why do some patients initially respond to drug treatment, only for it to stop working 18 months later?

The team, led by Dhananjay Suresh, Anandhi Upendran and Raghuraman Kannan at Mizzou’s School of Medicine, identified a hidden molecular “seesaw” involving two proteins inside cancer cells — AXL and FN14. When investigators try to block one protein to stop the cancer, the other one takes over, helping the tumor survive. To fix this, the team developed a new solution: a gelatin-based nanoparticle that can shut down both proteins at the same time.