The 2026 season of the Pharma.AI webinar series will showcase the ongoing AI revolution in life sciences, including the increased interest in the use of foundation models why specialized models remain essential for biology, chemistry, and translational research; How Pharma.AI brings together foundation models and scientific AI agents within a unified AI-driven workflow for drug R&D and scientific research; and how Insilico’s leading “AI trains AI” approach may enable foundation models to be better adapted for scientific and drug discovery applications, accelerating the evolution of AI decision-making systems.

Precise intracellular transport is essential for neuronal function, yet the exact mechanism of selective cargo delivery by motor proteins remains unclear. Now, researchers from Japan have reported that distinct kinesin-2 motor protein assemblies have specific cargo preferences. Their report mentions that the KIF3B/B/KAP3 kinesin complex specifically transports TRIM46 to the axon initial segment of a neuron. This discovery reveals the underlying mechanism of transport specificity in neurons and may help understand transport defect-related disorders.

Environmental enrichment (EE), which involves a combination of voluntary exercise and social interaction has been known to improve poststroke functional recovery. However, its effect on chronic inflammation and white matter pathology remains elusive. Now, a new study reveals that EE improves sensorimotor recovery after stroke while weakening correlation of infarct size with chronic inflammation and myelin damage. It also identifies TREM2-positive microglia in white matter as a potential cellular signal associated with improved functional recovery.

Research shows that living with friends may quietly be altering your gut bacteria. Research on a colony of tiny island birds in the Seychelles revealed they share more of their gut bacteria with the birds they spend the most time with. And the team say the same principle almost certainly applies to humans too. Dr Chuen Zhang Lee, from UEA’s School of Biological Sciences, said: “Translated into human terms, this means that cosy nights in, shared washing‑up duties, and even sitting close on the sofa may bring your microbiomes quietly closer together." The new research provides unusually clear evidence of how social closeness itself - not just shared environment - drives the exchange of gut bacteria.

Thanks to supercomputing, the research was able to analyze the activity of 20,000 genes in more than one million cells with unprecedented resolution, revealing different aging dynamics between men and women, which will be key to achieving precision medicine.

This study highlights that many characteristics of immune system aging that were previously considered universal actually present specific dynamics according to biological sex.

All processes such as wound healing, hair growth, and the replacement of old cells with new ones depend on cell division. During this process, chromosomes inside the cell must be evenly divided between two daughter cells. Even slight errors can lead to cellular abnormalities.

 

A research team at POSTECH (Pohang University of Science and Technology) has recently uncovered new clues suggesting that a protein called tau plays an important role in this highly regulated process. The findings were published in the international journal Nature Communications.