15-Dec-2025
An ‘illuminating’ design sheds light on cholesterol
University of PennsylvaniaPeer-Reviewed Publication
While high levels of cholesterol are linked to heart disease, stroke, and other health problems, this complex and vital molecule is found in every cell of the body and regulates crucial processes. By building light-controlled molecules that look and act like cholesterol, the University of Pennsylvania's Dirk Trauner have created a new set of tools allowing the researchers to toggle cholesterol’s biological activity on or off, paving the way for advanced therapeutics.
- Journal
- Journal of the American Chemical Society
- Funder
- Arnold and Mabel Beckman Foundation, NIH/National Institutes of Health, Novo Nordisk Fonden, Carlsberg Foundation