In a career defined by constant questioning, self-doubt can become an occupational hazard. Now, for the first time, a group of Cambridge scientists reveal the personal struggles they’ve faced – and continue to face – as they strive for success.

Scientists have developed a 3D, AI-based tool for viewing hearing cells. To understand hearing damage from noise and aging, and develop new treatments, scientists need detailed images of hair cells. The new VASCilia tool uses deep learning to accelerate sensory cell image processing and analysis.

Alliance Foundation Trials, LLC (AFT) today announced the publication of the pivotal phase III PATINA study (AFT-38) in the New England Journal of Medicine (NEJM), marking a major milestone for patients with hormone receptor–positive (HR+), human epidermal growth factor receptor 2–positive (HER2+) advanced breast cancer (ABC). The study’s results demonstrate that the addition of the CDK4/6 inhibitor palbociclib to standard first-line maintenance therapy significantly prolongs progression-free survival (PFS) by more than 15 months compared with standard therapy alone.

Deadly PM 2.5 air pollution that crosses state and national borders remains a serious global health issue. New research from the University of Notre Dame provides a tool to track responsibility and inform policy.