Dual-function biomaterials for postoperative osteosarcoma: Tumor suppression and bone regeneration
Peer-Reviewed Publication
Updates every hour. Last Updated: 15-Dec-2025 23:11 ET (16-Dec-2025 04:11 GMT/UTC)
Recently, a research team led by Professor Xie Huiqi at Sichuan University conducted a systematic review of dual-function biomaterials that combine anti-tumor and bone regeneration capabilities for postoperative osteosarcoma treatment. The article categorizes existing research findings into three design strategies: conventional dual-function strategies, enhanced anti-tumor strategies, and temporally regulated strategies. It further explores their design principles, therapeutic efficacy, and potential for clinical translation. This review aims to provide insights for establishing an integrated "anti-tumor and bone regeneration" treatment model and offers perspectives on future research directions in the field. The related work, entitled "Dual-Function Biomaterials for Postoperative Osteosarcoma: Tumor Suppression and Bone Regeneration," has been published in Research.
An Osaka Metropolitan University-led research team conducted a review that examined the theoretical foundations of Artificial Superintelligence and explored how misaligned AI systems could optimize for wrong objectives, leading to patient harm and systemic failures.
Six particular depressive symptoms when experienced in midlife predict dementia risk more than two decades later, finds a new study led by University College London (UCL) researchers.
Despite the limited performance, the project remains a proof of concept that pig skin can absorb medication delivered through a dissolvable microneedle patch. The research team also found that the patches work better on the neck than the ear. No adverse responses were observed at application sites, highlighting the safety and tolerability of the patches. Additionally, a new approach is being developed using the microneedle patch technology as a way to incorporate tattoos for animal tagging.