As U.S. cases rise, a nationally representative panel survey by the Annenberg Public Policy Center finds a small but significant drop in the proportion of the public that would recommend that someone in their household get the MMR vaccine, which protects against measles, mumps, and rubella. The survey finds drops in both the perceived safety and effectiveness of the MMR vaccine as well as two other vaccines.

A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific regulatory T cells (Tregs), the immune cells that play a central role in suppressing excessive immune responses. The findings, now published in Drug Delivery, may pave the way for next-generation therapies for autoimmune and allergic diseases, where unwanted immune activation must be precisely controlled.

Following the path towards innovation in education and health, the Department of Education and Specific Didactics of the Universitat Jaume I is developing Hort4Health. Under the direction of Mireia Adelantado Renau, lecturer in the Department of Didactics of Experimental Sciences, this leading project seeks to analyse and investigate in an interdisciplinary way the impact of integrating an eco-educational garden in the classrooms where students learn about health, sustainability and emotional well-being, thus offering a solid scientific basis on the benefits of these practices.

The Hort4Health project emerges in response to the growing need to promote healthy habits among young people, especially in an era where technology and sedentary lifestyles predominate and generate worrying figures. Through practical activities in the garden, students not only study about agriculture and ecology, but also experience the benefits of physical activity and contact with nature for their mental and physical health. Researcher Mireia Adelantado points out that in this way "scientific results will be obtained on the current healthy habits of the university community, completing the scarce previous literature on this subject in this population". This initiative has already involved more than a hundred pupils from the Early Childhood and Primary School Teacher degrees, who have participated in sessions designed to improve their emotional wellbeing, their connection with the environment and their understanding of the importance of an active and healthy life. Early results indicate a significant positive impact on the physical health of the participants and underline the potential of the garden as an innovative space for learning and wellbeing.

Clostridioides difficile is best known for causing antibiotic-related diarrhea, but a new review from China suggests it may also promote gastrointestinal cancers, especially colorectal cancer (CRC). The authors summarize clinical data, epidemiology, and tumor models showing how recurrent infection, toxins, inflammation, metabolism, and biofilms could reshape the colonic microenvironment. They argue chronic C. difficile infection as a potential driver of colorectal tumorigenesis and a promising biomarker, offering new insights for effective CRC prevention and therapy.

A Chinese Medical Journal review details innovative approaches to overcome solid tumor microenvironment barriers for CAR-T therapy, including vascular normalization, chemokine engineering, physical barrier targeting, and novel delivery methods, alongside key clinical challenges.