Medicine & Health
Updates every hour. Last Updated: 2-Jan-2026 19:11 ET (3-Jan-2026 00:11 GMT/UTC)
Human adipose tissue: a new source for functional organoids
Higher Education PressPeer-Reviewed Publication
Discover how human adipose tissue can be transformed into functional organoids representing all three germ layers—mesoderm, endoderm, and ectoderm—using a novel, streamlined method. This new study published in Engineering highlights the potential of adipose tissue for regenerative medicine, offering a scalable and clinically relevant alternative to traditional organoid generation techniques.
- Journal
- Engineering
AI-powered RNA drug development: a new frontier in therapeutics
Higher Education PressPeer-Reviewed Publication
Discover how AI is revolutionizing RNA drug development in a new article published in Engineering. Learn about the potential of AI to enhance RNA therapies, address current limitations, and unlock new opportunities for personalized medicine. Explore the future of AI-driven drug discovery and its impact on healthcare.
- Journal
- Engineering
Breast cancer hijacks immune alarm: turning defense into cancer-fueling inflammation
Science China PressPeer-Reviewed Publication
Researchers uncover a cunning new trick by which breast cancer cells evade immune attack. While the cGAS-STING pathway normally detects cytosolic DNA and activates anti-tumor immunity via IRF3-interferon signaling, aggressive tumors overexpress a long noncoding RNA, FAM83H-AS1, redirecting cGAS-STING signaling toward NF-κB-driven chronic inflammation that supports tumor growth. Critically, this shift creates a therapeutic vulnerability: NF-κB upregulates PD-L1, rendering these tumors highly susceptible to existing immunotherapies. This discovery reveals both a key mechanism for how cancer evades immunity and a promising way to fight back.
- Journal
- Science Bulletin
A soft, wireless implant treats inflammatory bowel disease by tapping into the body’s neural network
Science China PressPeer-Reviewed Publication
Scientists have created a groundbreaking, fully implantable neurostimulator made entirely of soft hydrogel to treat inflammatory bowel disease (IBD). Unlike traditional rigid and wired implants, this wireless device gently wraps around the splenic nerve. It receives power through the skin to deliver electrical pulses that calm gut inflammation by rebalancing the immune system. In animal studies, the device significantly alleviated colitis symptoms without causing scar tissue formation, paving the way for a new class of soft, bioelectronic therapies for chronic diseases.
- Journal
- National Science Review
Breakthrough in multiculture study of Sanghuang: secondary metabolite diversity reveals significant in vitro antidiabetic potential
Higher Education PressPeer-Reviewed Publication
A recent study comprehensively evaluated the secondary metabolite diversity and in vitro antidiabetic activity of Sanghuangporus quercicola under various culture conditions, highlighting the medicinal fungus’s immense potential for developing new antidiabetic drugs and functional foods.
- Journal
- Systems Microbiology and Biomanufacturing
Boosting sensitivity of cellulose pressure sensor via hierarchically porous structure
Shanghai Jiao Tong University Journal CenterPressure sensors are essential for a wide range of applications, including health monitoring, industrial diagnostics, etc. However, achieving both high sensitivity and mechanical ability to withstand high pressure in a single material remains a significant challenge. This study introduces a high-performance cellulose hydrogel inspired by the biomimetic layered porous structure of human skin. The hydrogel features a novel design composed of a soft layer with large macropores and a hard layer with small micropores, each of which contribute uniquely to its pressure-sensing capabilities. The macropores in the soft part facilitate significant deformation and charge accumulation, providing exceptional sensitivity to low pressures. In contrast, the microporous structure in the hard part enhances pressure range, ensuring support under high pressures and preventing structural failure. The performance of hydrogel is further optimized through ion introduction, which improves its conductivity, and as well the sensitivity. The sensor demonstrated a high sensitivity of 1622 kPa−1, a detection range up to 160 kPa, excellent conductivity of 4.01 S m−1, rapid response time of 33 ms, and a low detection limit of 1.6 Pa, outperforming most existing cellulose-based sensors. This innovative hierarchically porous architecture not only enhances the pressure-sensing performance but also offers a simple and effective approach for utilizing natural polymers in sensing technologies. The cellulose hydrogel demonstrates significant potential in both health monitoring and industrial applications, providing a sensitive, durable, and versatile solution for pressure sensing.
- Journal
- Nano-Micro Letters