31-Dec-2025
Natural polysaccharide-based microneedles: A promising frontier in cancer immunotherapy
KeAi Communications Co., Ltd.Peer-Reviewed Publication
This review highlights how natural polysaccharide-based microneedles (PMNs) are emerging as a transformative platform for cancer immunotherapy. We report their unique dual role in drug delivery and immune regulation, the innovative use of 3D printing for precision fabrication, and their smart responsiveness to the tumor environment. By integrating biocompatibility, enhanced drug loading, and controlled release, polysaccharide-based microneedles (PMNs) offer a promising strategy to overcome challenges in traditional cancer immunotherapies, potentially supporting the development of more effective and personalized treatments.
- Journal
- Glycoscience & Therapy
- Funder
- National Natural Science Foundation of China, Oriental Scholars of Shanghai Universities, Jiangxi Province Thousand Talents Program, Shanghai Rising-Star Program, Shanghai Sailing Program, Organizational Key Research and Development Program of Shanghai University of Traditional Chinese Medicine, CAMS Innovation Fund for Medical Sciences, Key project at central government level: The ability establishment of sustainable use for valuable Chinese medicine resources, High level Key Discipline of National Administration of Traditional Chinese Medicine