Does iron accumulation in the brain contribute to neurodegeneration?
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Jun-2026 16:16 ET (25-Jun-2026 20:16 GMT/UTC)
Salk scientists explore long-standing mystery of why iron that builds up in neuronal cells becomes harmful over time in neurodegenerative diseases like Alzheimer’s and Parkinson’s, finding a new cellular process, named chronoferroptosis, wherein chronic iron dysregulation in neurons makes them more vulnerable to stressors. The study complements other ongoing research at Salk to design compounds that inhibit this pathway, and could be a promising future avenue for creating therapies that boost resilience in aging brains.
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