Medicine & Health
In a recent review article for the journal Cancers, Masmudur Rahman and Grant McFadden describe a class of viruses that act to combat rather than cause deadly disease. Such oncolytic viruses as they are known, have a remarkable ability to target and destroy cancer cells, while leaving healthy cells untouched.
What The Study Did: This study found an increase from 2011 to 2017 in older adults receiving help at home with activities of daily living after a hospital discharge, results that may reflect the shifting location and payment for postdischarge care away from Medicare-reimbursed inpatient postacute care facilities.
- JAMA Network Open
“We believe this change is critical to how the bacterium causes disease and is something that we can exploit for both therapeutic and diagnostic purposes,” said Brandon Jutras, an assistant professor of Biochemistry in the College of Agriculture and Life Sciences and an affiliated faculty of the Fralin Life Sciences Institute and the Center for Emerging, Zoonotic, and Arthropod-Borne Pathogens.
- Nature Microbiology
In mice with high-risk neuroblastoma, tumors disappeared in response to a new combination treatment with precision medicines, a recent study from University of Gothenburg researchers shows. This is a vital step toward a potentially curative treatment for a form of cancer affecting young children that is currently difficult to treat.
- Nature Communications
The National Cancer Institute has awarded Mount Sinai researchers $3.15 million in grant funding to assess the potential of a multidisciplinary drug development platform to identify new biological targets for precision-based therapeutics for hepatocellular carcinoma (HCC). The platform includes precision mouse models, tumor 3D organoids, and a proprietary library of small molecule inhibitors.
The German Research Foundation (DFG) has approved the establishment of a new Collaborative Research Center (CRC) in the field of materials science, in which Johannes Gutenberg University Mainz (JGU) is participating with a pioneering subproject. In addition, the existing CRC 1292 coordinated by JGU was approved for a further funding period of four years.
- Deutsche Forschungsgemeinschaft (DFG)