Tirzepatide, a new injectable weight-loss drug with the trade name Zepbound, reduced the risk of diabetes in patients with obesity and prediabetes by more than 90% over a three-year period, compared with placebo, according to the results of a new study led by investigators at Weill Cornell Medicine, NewYork-Presbyterian, Yale School of Medicine and other institutions.

About The Study: This cohort study among individuals participating in a weight loss program found that nearly half of those consuming alcohol at baseline decreased their alcohol use after anti-obesity medication initiation. There may be properties of anti-obesity medications that lead to reduced use. For example, naltrexone decreases cravings for alcohol and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may attenuate the rewarding effects of alcohol, similar to food. 

University of Toronto researchers have developed a new computational method to study how chromosomes within human cells are organized. The method could help advance precision medicine by shedding light on how chromosomal re-organization leads to disease development.   

Using antibiotics alone to treat children with uncomplicated appendicitis is a cost-saving alternative to surgery.

Challenging the traditional view of consumption as an isolated, immediate event, Stefania Minardi of HEC Paris and Andrei Savochkin of Bocconi University’s Department of Decision Sciences explore the idea that experiences can create lasting mental imprints that affect future well-being, and that this effect is taken into account when people make current decisions about whether to go for certain experiences or puchase goods or services. In their recent paper, “Time for Memorable Consumption”, published in Games and Economic Behavior, they seek to incorporate this idea into the way economic decision-making is understood and modeled. By integrating insights from psychology with economic theory, the authors provide a new quantitative framework to capture how “memorable consumption” shapes long-term satisfaction and decision patterns.