Bentham Science announces the release of an essential reference for researchers, educators, and industry professionals engaged in drug discovery and experimental pharmacology. Zebrafish Models for Experimental Pharmacology: A Handbook presents a clear, practical, and methodologically rich approach to harnessing the Zebrafish as a powerful model organism in biomedical research.

Inhibiting a specific gene, MET, in combination with standard chemotherapy and immunotherapy, enhances treatment efficacy and limits tumor growth in small cell lung cancer (SCLC). The study, led by the Hospital del Mar Research Institute, analyzed the effect of MET inhibition in mouse models and studied gene expression in patient tumor samples. The results are published in Cell Reports Medicine. Researchers aim to pursue this line of research with a clinical trial involving patients.

A new systematic review of 172 studies including data from over 12 million adolescents across 166 countries reveals that while cross-national adolescent mental health research including low- and middle-income countries has expanded significantly, large gaps remain in global representation.

The German Research Foundation (DFG) is funding LMU scientist Anne-Laure Boulesteix: How can we improve research on statistical methods, asks the biostatistician, and thereby also improve their use?