Research has always been critical to improving patient lives. That is why the American Thoracic Society (ATS), a Coalition to Transform Clinical Trial Engagement Steering Committee (CTCTE) member, is proud to be one of seven organizations partnering with the Foundation for Sarcoidosis Research (FSR) to make it easier for patients, including those with chronic lung disease, to join research. The Champions for Change – Paid Time Off (PTO) Initiative is a national effort to reduce job-related barriers to clinical trial participation by partnering with employers to provide PTO for employees enrolling in trials.

By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis–an integrated gene signature for ferroptosis. They evaluated the associated genes in both mice and human liver injury systems, validating the potential use of iFerroptosis as a biomarker for hepatic ferroptosis. By highlighting the role of ferroptosis in liver injuries, this study offers insights into unique therapeutic targets for ferroptosis.