Inherited metabolic liver diseases (IMLDs) have complex etiologies and vary widely in clinical presentation, with a significant overall incidence. With the advancements in diagnostic and treatment technologies, an increasing number of children with inherited metabolic diseases are surviving into adolescence and adulthood. These advancements have improved our understanding of the IMLD disease spectrum and clinical outcomes. This study aimed to analyze changes in the disease spectrum and epidemiological characteristics of inherited metabolic liver diseases (IMLD) over the past 20 years in two specialized liver disease hospitals in northern China.

A healthy diet outperforms fecal transplants in restoring and protecting the gut microbiome, finds new research published in Nature by the Simons Foundation’s Joy Bergelson and collaborators at the University of Chicago. The results point to new strategies for treating gastrointestinal disorders, recovering from antibiotics and protecting against pathogens.

A research paper by scientists at Kyushu University presented a novel needle-free reagent injection method that improves the depth of reagent injection by reflecting shock waves through microbubble dynamics.