Findings from a randomised and blinded clinical trial investigating repeated ketamine infusions for treating depression have revealed no extra benefit for ketamine when added onto standard care for people admitted to hospital for depression. The paper is published in the journal JAMA Psychiatry 

Authors of a new Pediatrics commentary titled “Ethical Implications of Study Terminations” examine what happens when clinical research trials end abruptly—particularly those that involve children and adolescents, who are already underrepresented in research. They argue that such sudden closures can break trust and harm participants, especially when the research involves young people. They also note that these actions conflict with long-standing ethical principles outlined in the Belmont Report—federal guidelines published in 1979 that outline three main principles for human research: respect for persons, beneficence, and justice.

Social support can be the difference between life and death for children struggling with adverse childhood experiences (like the death or absence of a parent, substance abuse in the household or community violence) at home, according to a new University of Georgia study.

(Boston)—Jillian C. Shipherd, PhD, professor of psychiatry at Boston University Chobanian & Avedisian School of Medicine and an affiliate psychologist at the Women’s Health Sciences Division of the National Center for PTSD at VA Boston Healthcare System, has received a 2025 Charles Silverstein Lifetime Achievement Award in Social Justice from the Association for Behavioral and Cognitive Therapies (ABCT). The award is given to individuals who have made significant and sustained lifetime contributions to advancing social justice initiatives over many years.

An international consortium of researchers has created the largest-ever database compiling records of brain activity during sleep and dream reports. One of the first analyses of the database confirmed that dreams do not occur only during REM sleep, but also during deeper and calmer NREM stages. In these cases, brain activity resembles wakefulness more than deep sleep, as if the brain were “partially awake”.