Monitoring cognitive brain function before and after spaceflight: feasibility of brain vital signs
Peer-Reviewed Publication
Updates every hour. Last Updated: 13-Nov-2026 04:16 ET (13-Nov-2026 09:16 GMT/UTC)
As humanity enters the era of long‑term crewed deep‑space exploration, understanding the brain’s adaptive mechanisms to extreme environments such as microgravity and radiation has become a critical issue in space medicine. Previous studies using magnetic resonance imaging have revealed structural brain plasticity after spaceflight, including ventricular expansion and changes in grey matter volume. However, knowledge of dynamic changes at the neurophysiological level remains limited, and most existing evidence comes from group‑level analyses of long‑duration missions (e.g., six months), leaving the specific neurofunctional impact of short‑duration missions on individuals unclear. Conventional neuroimaging equipment is bulky and cannot be used in orbit. In contrast, electroencephalography (EEG) is portable, low‑cost, and repeatable, and has shown sensitivity in neurological conditions such as concussion, but its application in the extreme spaceflight environment has not been reported. Therefore, validating the feasibility of portable EEG technology for monitoring individual brain function before and after short‑duration spaceflight holds significant practical value for building future in‑orbit brain health assessment systems in deep‑space exploration.
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