Chemotherapy-induced nausea and vomiting (CINV) represents one of the most distressing and debilitating side effects experienced by cancer patients undergoing treatment, significantly impacting quality of life, treatment adherence, and overall therapeutic outcomes. Neurokinin-1 receptor antagonists (NK1RAs) have emerged as cornerstone agents in the modern management of CINV, particularly for delayed-phase symptoms that occur 24-120 hours after chemotherapy administration. These agents target substance P binding to NK-1 receptors in both central and peripheral nervous system pathways, addressing the complex neurotransmitter mechanisms underlying CINV pathophysiology.

With the continuous development of drug delivery technology, natural polyphenol self-assembled drug delivery systems (DDS) have become a research focus due to their unique advantages. Polyphenols can not only serve as drugs themselves but also as components of self-assembled drug delivery systems, broadening their application in the field of drug delivery. This article reviews the mechanisms of interactions between polyphenols and between polyphenols and other molecules, and analyzes the process of constructing drug delivery systems with polyphenols. At the same time, it deeply explores the multiple functions of polyphenol self-assembled complexes in drug delivery, such as enhancing drug efficacy, achieving precise targeted delivery, and overcoming biological barriers, highlighting their great potential in enhancing drug efficacy and reducing side effects. In addition, several advanced characterization and preparation techniques are introduced and discussed, which will help to deeply understand and evaluate the structure and performance of polyphenol self-assembled delivery systems, promoting their further development. Finally, the challenges and future intelligent manufacturing strategies of polyphenol self-assembled complexes are summarized.

Recently, Professor Shijian Zheng and Associate Professor Kaixiang Lei from Hebei University of Technology, in collaboration with Professor Lin Li and Dr. Xunzhu Zhou from Wenzhou University, published a research paper titled "Synergistic biphasic engineering and dual-site high-entropy doping enable stable sodium storage in layered oxide cathodes" in the journal Nano Research. In this study, a novel P2/O3 biphasic high-entropy oxide cathode material (Na_0.88K_0.02Ni_0.24Li_0.06Mg_0.07Fe_0.1Mn_0.41Ti_0.1Sn_0.02O₂, HEO) for sodium-ion batteries was successfully synthesized. By integrating biphasic engineering with a high-entropy strategy, this material effectively suppresses irreversible phase transitions, significantly enhances particle integrity and structural stability, and simultaneously improves the diffusion kinetics of Na⁺. Experimental results demonstrate that the cathode material maintains a high capacity retention of 82.68% after 1000 cycles, exhibiting its outstanding cycling stability.

Sulfide-based all-solid-state lithium metal batteries (ASSLMBs) are promising for high-energy-density and safe energy storage. But the poor compatibility of sulfide electrolytes with both high-voltage cathodes and lithium metal anodes hinders their practical application. Here, Professor Xie Jia's group from Huazhong University of Science and Technology discloses a fluorine-nitrogen synergistic interfacial engineering strategy by modifying Li5.5PS4.5Cl1.5 (LPSC) with lithium bis(trifluoromethanesulfonyl)imide (LiTFSI). The modified LPSC electrolyte shows a high ionic conductivity of 2.88 mS/cm. Moreover, LiTFSI induced dual-functional interphases, a fluorine-rich CEI (LiF/LixPOyFz) and a fluorine-nitrogen composite SEI (Li3N/LiF/LixPOyFz), contributing to high oxidation stability (LiNi0.8Co0.1Mn0.1O2//LiIn battery retains 107% capacity retention after 13000 cycles at 15 C) and excellent lithium dendrite inhibition ability (Li//Li: CCD 3.4 mA/cm2, stably cycling 2600 h at 0.5 mA/cm2). As a result, the LiNi0.8Co0.1Mn0.1O2//Li cell with modified electrolyte demonstrates 1000 stable cycles at a high cut-off voltage of 4.5 V and wide-temperature adaptability (-20~50 ℃). This work shows a facile and effective method for constructing long-life high-energy-density sulfide based ASSLMBs.

This study proposes a mechanism-data dual-driven framework to address the challenge of balancing water conservation, carbon emission reduction, and aquatic ecosystem preservation in China's industrial sector at minimal cost. It involves developing hybrid models for water-use and treatment processes and establishing a superstructure optimization model. This model identifies the optimal pathway for simultaneous water saving and carbon mitigation, supporting cost-effective decisions for industrial park water network optimization. Case studies confirm the framework's effectiveness in balancing economic and environmental benefits.

As the number of wireless applications and devices grows, higher standards for the quality of service and navigation performance of mobile networks are required. Numerous critical applications, including unmanned aerial vehicles, internet of things, digital twin, and military systems, require reliable communication and accurate navigation services. To meet these requirements, the development of the sixth generation (6G) network is necessary. 6G networks provide seamless 3-dimensional coverage in space–air–ground–sea area, as well as deep coupling of communication, sensing, and computation. 6G networks will be combined with low Earth orbit (LEO) satellites to construct a universal and intelligent integrated system of communication, sensing, and computing by utilizing the benefits of LEO satellites, such as miniaturization, modularity, large bandwidth, low latency, and wide area coverage. One of the critical construction tasks in this system is the integration of communication and navigation (ICAN), which can break the limitations of the global navigation satellite system, provide high-precision, robust navigation capability, and enable high- quality communication services.