Detecting Alzheimer's with DNA aptamers—new tool for an easy blood test
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Apr-2026 16:16 ET (22-Apr-2026 20:16 GMT/UTC)
The single-stranded DNA molecules developed by researchers using the SELEX technology could transform blood testing for Alzheimer's biomarkers. These synthetic aptamers target neurofilament light chain (NfL), a structural protein component of nerve cells, that is released into the bloodstream upon neuronal injury. These aptamers exhibit binding strength and selectivity comparable to anti-NfL antibodies used in current tests, while being more economical to produce and reliable, opening the door to affordable, diagnostic biosensors.
Motor imagery or imagined limb movements can power brain–computer interface (BCI) devices, such as prostheses and wheelchairs, supporting rehabilitation for people with neuromusculoskeletal disorders. However, conventional decoding methods often fail to capture complex spatiotemporal variations in electroencephalography signals. Now, researchers from Chiba University, Japan, have developed a novel Embedding-Driven Graph Convolutional Network that decodes dynamic patterns in brain activity, offering improved adaptability and generalizability to advance next-generation BCI technologies.
In a significant advancement for lab-on-chip technology, IBEC researchers in the frame of the European project BLOC, have demonstrated the first integration of a benchtop nuclear magnetic resonance (NMR) spectrometer with a microfluidic cell culture platform capable of real-time metabolic monitoring, made feasible by employing quantum-enhanced NMR techniques to dramatically increase signal sensitivity.
First study to use crowdsourced comments to assess effects of heat underground. Researchers collected comments from X and Google Reviews published between 2008 and 2024. Study focused on subway systems in Boston, New York and London. As above-ground temperatures rise, below-ground thermal complaints increase. Knowing when people are uncomfortable could inform targeted interventions.