Most japonica rice varieties possess similar alleles for grain size, producing short and wide grains.

The gs9^ko allele has a widely applicable effect on grain appearance improvement. The increased leaf angle of the gs9^ko allele does not affect its improvement effect.

A rapidly growing field is piezoresistive sensor for accurate respiration rate monitoring to suppress the worldwide respiratory illness. However, a large neglected issue is the sensing durability and accuracy without interference since the expiratory pressure always coupled with external humidity and temperature variations, as well as mechanical motion artifacts. Herein, a robust and biodegradable piezoresistive sensor is reported that consists of heterogeneous MXene/cellulose-gelation sensing layer and Ag-based interdigital electrode, featuring customizable cylindrical interface arrangement and compact hierarchical laminated architecture for collectively regulating the piezoresistive response and mechanical robustness, thereby realizing the long-term breath-induced pressure detection. Notably, molecular dynamics simulations reveal the frequent angle inversion and reorientation of MXene/cellulose in vacuum filtration, driven by shear forces and interfacial interactions, which facilitate the establishment of hydrogen bonds and optimize the architecture design in sensing layer. The resultant sensor delivers unprecedented collection features of superior stability for off-axis deformation (0–120°, ~ 2.8 × 10^–3 A) and sensing accuracy without crosstalk (humidity 50%–100% and temperature 30–80 °C). Besides, the sensor-embedded mask together with machine learning models is achieved to train and classify the respiration status for volunteers with different ages (average prediction accuracy ~ 90%). It is envisioned that the customizable architecture design and sensor paradigm will shed light on the advanced stability of sustainable electronics and pave the way for the commercial application in respiratory monitory.

This paper expounds on the development status and relevant works of control and guidance methods of the aerospace vehicle in recent years. The control difficulties and the solutions in the related results are introduced briefly. Moreover, the guidance methods are then expounded in detail according to the flight phases of the whole flight mission. Guidance methods are usually included in each phase, and the corresponding trajectory design theories are also introduced where necessary. In addition, the potential future development direction prospects. Based on the above, a brief conclusion is then made as a summary.

Targeting the issue of immunosuppression in the tumor microenvironment (TME) during hepatocellular carcinoma (HCC) immunotherapy, this study was the first to confirm that melarsoprol (MEL), an arsenic-containing drug, activates the cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS)-stimulator of interferon genes (STING) pathway in tumor cells and induces an antitumor immune response . However, high-dose MEL excessively activates the pro-tumorigenic cytokine tumor necrosis factor-α (TNF-α), which impairs the immunotherapeutic efficacy. To address this, a poly(D,L-lactic-co-glycolic acid) (PLGA)-based nanoparticle (NP) was prepared in this study for the co-delivery of MEL and lenalidomide (LEN), a TNF-α inhibitor. Through erythrocyte membrane camouflage and aminoethyl anisamide (AEAA)-targeted modification, the nanoparticle was precisely enriched in HCC tissues. It significantly reversed the immunosuppressive TME and achieved antitumor effects in two mouse models of HCC . This study provides a novel strategy for the chemoimmunotherapy of HCC.

Microplastics, tiny bits of plastic less than 5 millimeters in size, are now found in our air, food, water, and even inside the human body, according to new research led by scientists from China and the United States. The study, published in Carbon Research, urges scientists and policymakers to take immediate steps to understand and address potential health risks linked to widespread plastic pollution.