Professor Ying-Wei Yang's research group at Jilin University successfully constructed an azobenzene-modified metal-organic framework (MOF)-based nano-impeller platform using a dimensional engineering strategy. They synthesized two-dimensional layered Zn-Azo-MOF-1 and three-dimensional network Zn-Azo-MOF-2 with the same composition but different dimensions. They found that the photoisomerization efficiency of the two-dimensional framework (cis isomer content 33%) was an order of magnitude higher than that of the three-dimensional framework (3%). Mechanical grinding triggered interlayer slip in the two-dimensional structure, breaking the spatial confinement and activating efficient photoisomerization. Analysis of rotational energy barriers and framework-ligand interactions revealed the mechanism by which dimensionality and mechanical activation synergistically regulate the photo-switching dynamics. The constructed two-dimensional Zn-Azo-MOF-1 achieved 99% cargo release within 50 minutes under alternating UV-Vis irradiation, successfully extending the nano-impeller function from an amorphous platform to a crystalline platform, providing a dimensional engineering design principle for the programmable switching behavior of stimulus-responsive materials. The article was published as an open access Research Article in CCS Chemistry, the flagship journal of the Chinese Chemical Society.

Scientists have developed a 3D, AI-based tool for viewing hearing cells. To understand hearing damage from noise and aging, and develop new treatments, scientists need detailed images of hair cells. The new VASCilia tool uses deep learning to accelerate sensory cell image processing and analysis.

No ears, no problem! The tobacco hornworm caterpillar, a common garden pest, can actually detect airborne sound via microscopic hairs on its body, according to a team of faculty and graduate students at Binghamton University, State University of New York. The research could have implications for improving microphone technology.

Multicellularity is one of the most profound phenomena in biology, and relies on the ability of a single cell to reorganize itself into a complex organism. It underpins the diversity in the animal kingdom, from insects to frogs, to humans. But how do cells establish and maintain their individuality with such precision? A team led by Jan Brugués at the Cluster of Excellence Physics of Life (PoL) at Dresden University of Technology has uncovered fundamental mechanisms that shed light on this question. The findings, now published in the scientific journal Nature, reveal how cells establish physical boundaries through an inherently unstable process, and how different species have evolved distinct strategies to circumvent this process.