New study examines how coaches are using data and technology to maximize player performance and safety. 

Reporting in Science, researchers at UC Santa Barbara, UCSF and the University of Pittsburgh have developed a new workflow for designing enzymes from scratch, paving the way toward more efficient, powerful and environmentally benign chemistry. The new method allows designers to combine a variety of desirable properties into new-to-nature catalysts for an array of applications, from drug development to materials design. This research is the result of a collaborative effort between the DeGrado lab at UCSF, the Yang lab at UCSB and the Liu lab at the University of Pittsburgh.

Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level. This advance could help clinicians identify certain diseases, streamline the process of drug discovery, and give biologists new insights into the effects of protein mutations.