The growing threat of antimicrobial resistance (AMR) calls for effective solutions such as phage therapy. In China, phage therapy has been implemented in over 30 hospitals, treating more than 500 patients with multidrug-resistant infections. Phage therapy can currently be developed through two pathways: as a novel biomedical technology or as a new drug. However, regulatory ambiguity persists due to a lack of standardized quality criteria and clear approval frameworks. This article proposes a "standards first, pathway pilots, and industry cultivation" strategy. Key recommendations include developing national quality control guidelines for therapeutic phage preparations and clarifying the detailed guidelines for approval policies for new biomedical technologies, biologics, and advanced therapy medicinal products (ATMPs). These efforts aim to enable safe and effective clinical translation, positioning China as a frontrunner in phage therapy and making significant contributions to the global response against AMR.

The intravenous infusion of mesenchymal stem cells from family donors is safe and improves symptoms such as pruritus (itching), sleep disturbances, and fatigue associated with Recessive Dystrophic Epidermolysis Bullosa (RDEB), popularly known as "butterfly skin". This is one of the primary conclusions of a clinical trial conducted by researchers from the Universidad Carlos III de Madrid (UC3M), the Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT) of the Ministry of Science, Innovation and Universities, the Fundación Jiménez Díaz Health Research Institute (IIS-FJD), the CIBER Rare Diseases (CIBERER), and the La Paz University Hospital in Madrid.

This study explores how healthy young adults’ brains adapt to visual occlusion during walking. Using Bangerter foils, resting-state functional magnetic resonance imaging (rs-fMRI), and pattern-reversal visual evoked potentials (PR-VEPs), it finds that walking activated key visuomotor pathways. Visual impairment strengthens functional connectivity between the right precentral and middle frontal gyri as compensation. The findings offer new potential targets for motor rehabilitation in low-vision populations.

A newly identified molecular pathway helps maintain the integrity of the bones in the skull and the face. Using mouse models, the study showed that loss of PTH1R signaling in periodontal cells triggers abnormal cementum overgrowth, severe periodontal ligament damage, and pathological tooth-bone fusion known as ankylosis. The findings uncover previously unknown mechanisms regulating adult periodontal tissue maintenance and may support future therapies for eruption disorders, ankylosis, and other periodontal diseases linked to abnormal mineralization.

Rising carbon dioxide emissions pose a major global challenge. Electrochemical CO₂ reduction using copper-based electrocatalysts offers a promising and sustainable route to convert CO₂ into valuable multi-carbon fuels and chemicals. However, achieving high stability and selectivity remains difficult. Researchers have now examined advanced catalyst design strategies that integrate atomic-level engineering, machine learning and in situ analysis to enhance performance and enable scalable carbon recycling systems significantly.