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Updates every hour. Last Updated: 22-Oct-2025 05:11 ET (22-Oct-2025 09:11 GMT/UTC)
In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The results, published June 24th in the open-access journal PLOS Biology, offer new hope for people with rare genetic conditions.
A groundbreaking study in PLOS Biology from researchers at Harvard University, offers a fresh and compelling answer to the fundamental evolution mystery of how mammals went from sprawling like lizards to upright; revealing the path to upright posture wasn’t linear, but full of unexpected detours, evolutionary experimentation, and dramatic anatomical upheaval.
The transition from sprawling (reptile-like) to more upright (parasagittal) posture and locomotion was a transformative event in mammalian evolution. A study published June 24th in the open-access journal PLOS Biology by Dr. Robert Brocklehurst and Professor Stephanie Pierce at Harvard University, USA and colleagues suggests that parasagittal posture evolved via an indirect, dynamic, and radiating process.
A trade-off between tooth size and jaw mobility has restricted fish evolution, Nick Peoples at the University of California Davis, US, and colleagues report June 24th in the open-access journal PLOS Biology.