An international collaboration featuring the University of Vienna and the University of Wisconsin-Madison (USA) has led to the first-ever chromosome-level genome assembly of a sea spider (Pycnogonum litorale). The genome informs about the development of the characteristic sea spider body plan and constitutes a landmark for revealing the evolutionary history of chelicerates in general. The study was recently published in BMC Biology.

Pituitary neuroendocrine tumors (PitNETs) are usually removed by endoscopic endonasal surgery (EES). However, surgical management of giant and irregular pituitary neuroendocrine tumors (GIPitNETs) with EES is often challenging, due to their large size and irregular shape. An alternative approach is combined endoscopic endonasal and transcranial surgery (CECS). Now, researchers compare the efficacy and outcome of both surgical techniques for treating GIPitNETs and found that CECS is safe and effective with comparable complication rates.

Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system’s natural defenses against cancer. This pathway, which plays a key role in helping the body defend against potential pathogens, can be leveraged to trigger an innate immune response that targets cancer cells. However, a study published July 3 in the journal Nature Chemical Biology, led by biochemist Lingyin Li (Bluesky: @lingyinli.bsky.social), is spearheading a new school of thought.

An international research team led by scientists from the University of Vienna has uncovered new insights into how specialized cell types and communication networks at the interface between mother and fetus evolved over millions of years. These discoveries shed light on one of nature's most remarkable innovations – the ability to sustain a successful pregnancy. The findings have just been published in Nature Ecology & Evolution.

Researchers at the School of Chinese Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), have made a breakthrough in the treatment of autoimmune diseases. Their study reveals that combining the active ingredient extracted from the traditional Chinese medicine Astragalus membranaceus (huang qi) with the widely used Western drug methotrexate (MTX) can effectively reduce chronic inflammation in autoimmune diseases such as systemic lupus erythematosus and Sjögren’s disease. This study provides a new solution to address the drug resistance and the side effects caused by long-term medication. The research findings were published in two leading international journals, Acta Pharmacologica Sinica and Journal of Leukocyte Biology, where they were featured as cover stories.

Scientists have conducted a study of the predatory behavior of sharks in deep-sea ecosystems. This research provides insights into the behavior and distribution range of Pacific sleeper sharks. The research is published in the journal Ocean-Land-Atmosphere Research on June 1, 2025.

Neuroform Atlas Stent (NAS) is used in treating localized dilation of blood vessels in the brain. The stent is designed for placement in vessels of 2.0─4.5 mm diameter. However, studies that assess whether NAS is equally effective in smaller blood vessels are limited. Researchers from China addressed this critical clinical question, and report that even in smaller vessels of diameter less than 2.5 mm, NAS-assisted coiling led to fewer complications and favorable short-term outcomes.