IRB Barcelona coordinates MD4SB, a project to boost dynamic description in structural biology
Grant and Award Announcement
Updates every hour. Last Updated: 2-Nov-2026 02:16 ET (2-Nov-2026 07:16 GMT/UTC)
MD4SB will establish an infrastructure for the dynamic description of biological macromolecules, connecting three major European Research Infrastructures (Instruct-ERIC, ELIXIR, and EU-OPENSCREEN ERIC) with three of Europe's largest supercomputing centres (BSC-CNS, CINECA, and JSC).
The project will facilitate the use of molecular simulations to understand how biomacromolecules function, advance the molecular description of diseases, and accelerate drug discovery.
Coordinated by IRB Barcelona, the project brings together 25 partners across 8 countries and incorporates Almirall, Sanofi, and other pharmaceutical companies to provide feedback and evaluate the practical usefulness of the platform in industrial settings. The IRB Barcelona spin-off company Nostrum Biodiscovery will bridge the gap between academic groups and pharmaceutical companies.
Researchers developed a simpler and more cost-effective method to measure DNA-bound phosphorus, a biologically active form of phosphorus linked to soil microbes. The study found that this hidden nutrient pool is closely associated with microbial activity and soil fertility. The findings could support more sustainable phosphorus management and agricultural production.
Physicists have long wondered whether the fundamental laws of nature contain freely adjustable external “dials.” A researcher at Kyushu University and collaborators have shown, under certain assumptions, that continuous parameters in conformal field theories can be generated by operators within the theory itself. The findings support Einstein’s idea that apparent free parameters in quantum gravity should be explained by dynamical fields rather than chosen externally.
A team from Tsinghua University reports Au–TiO₂ metasurfaces that convert visible light into singlet oxygen at high speed and extremely high local density. By combining quasi-BIC field confinement with hot-carrier transfer across an ultrathin interface, the device produces molar-level singlet oxygen locally within seconds, which is surprisingly ~10⁶ times that achieved by conventional approaches. Besides, the on-chip generator enables wavelength- and pixel-selective cytotoxicity for targeted tumor cell killing in photodynamic therapy.
Every time an autonomous drone dives to explore the ocean floor, the very armor designed to protect it simultaneously blinds its sonar. In International Journal of Extreme Manufacturing, Chinese researchers have solved this long-standing engineering paradox by inventing a soft, custom-molded acoustic "contact lens" that actively corrects outgoing sound waves before they pass through the drone's protective shell.
Harvard researchers have built a device called a pico-calorimeter that directly measures heat signals from small groups of living cells.