Researchers have demonstrated the feasibility of a morphological-based approach to interpreting spatial transcriptomic (ST) data, helping to improve understanding of the lesions that occur in chronic kidney disease (CKD), at both the cellular and molecular levels. A recent study in The American Journal of Pathology, published by Elsevier, details how this new method could lead to the identification of new biomarkers and therapeutic strategies for patients.

Messenger RNA can travel between different types of stem cells through tunnel-like structures, as revealed by a new study. By studying interactions between mouse and human stem cells, they discovered that this RNA transfer can reprogram human cells to an earlier developmental state. This groundbreaking finding not only sheds light on an underexplored form of cellular communication but also suggests promising applications in regenerative medicine without using artificial genetic modifications or external chemicals.