21-Mar-2025 Can electricity flow without electrons? DOE/US Department of Energy Scientists have long held that electricity is carried by individual electrons with discrete charges moving in a metal, even in the case of electrons clumped into quasiparticles. However, “strange metals” fail to obey this paradigm. Researchers have observed a radical quantum blurring of electrons in strange metal into a featureless liquid, potentially pointing toward a new theory of electrical transport. Journal Science
21-Mar-2025 Core samples from Greenland's seabed provide first historical overview of plastic pollution University of Copenhagen - Faculty of Science By coring the seabed at 850 m water depth in Disko Bay off Greenland's west coast, researchers from the University of Copenhagen have obtained the first historical record of plastic pollution in Greenland. The new data suggest a link to local socio-economic development and represent a step towards developing a common method for analyzing and mapping global microplastic pollution. Journal Nature Communications
21-Mar-2025 Fingertip sweat shows whether tuberculosis patients are taking medication properly Universitair Medisch Centrum Groningen Sweat from a fingertip can be used to test whether tuberculosis (TB) patients are taking their medication properly. Until now, this could only be done by pricking blood. On March 24 it's World Tuberculosis Day. Journal International Journal of Antimicrobial Agents
21-Mar-2025 A review of latest tools and technologies in pharmaceutical research KeAi Communications Co., Ltd. This comprehensive review analyzes cutting-edge tools and technologies in modern pharmaceutical research, focusing on artificial intelligence, multi-omics technologies, and experimental methods. The study highlights how computational methods enhance drug discovery efficiency, while omics technologies provide systematic frameworks for investigating drug mechanisms. The integration of these advanced approaches has enabled more diverse and personalized treatment strategies, though challenges remain in drug development complexity, cost-effectiveness, and operational feasibility. Journal Current Pharmaceutical Analysis
21-Mar-2025 Genetic diversity and conservation insights for Phoebe bournei: A study using EST-SSR molecular markers Maximum Academic Press A research team using EST-SSR molecular marker technology reveals vital information on the genetic diversity and structure of nine natural populations of Phoebe bournei, providing a scientific foundation for the conservation and sustainable use of its germplasm resources. Journal Tropical Plants
20-Mar-2025 New pilot study shows deep brain stimulation may reduce severe self-injurious behavior in children with autism spectrum disorder Elsevier Severe self-injurious behavior in children with autism spectrum disorder (ASD) poses a significant risk of permanent physical injury. Not all children respond to behavioral therapies. Findings from a pilot trial in Biological Psychiatry, published by Elsevier, show that deep brain stimulation (DBS) of the nucleus accumbens (NAc), the reward-related region of the brain, in children with severe self-injurious behavior and ASD is relatively safe and feasible and may have notable benefits. Journal Biological Psychiatry Funder The Hospital for Sick Children (SickKids)
20-Mar-2025 Evaluation of inhaled technosphere insulin plus insulin degludec for adults with type 1 diabetes Mary Ann Liebert, Inc./Genetic Engineering News A new study in the peer-reviewed journal Diabetes Technology & Therapeutics (DTT) concluded that inhaled technosphere insulin (TI-Afrezza) should be considered as an option for individuals with type 1 diabetes who want an alternative to using an insulin pump or multiple daily injections (MDI) for insulin delivery. Journal Diabetes Technology & Therapeutics
20-Mar-2025 Cardiovascular and renal biomarkers in overweight and obese adults with type 1 diabetes treated with tirzepatide Mary Ann Liebert, Inc./Genetic Engineering News In a new study in the peer-reviewed journal Diabetes Technology & Therapeutics (DTT), investigators evaluated biomarkers for cardiovascular disease (CVD) and diabetic kidney disease (DKD) in overweight and obese (OW/OB) adults with Type 1 Diabetes treated with tirzepatide, a dual-incretin approved for use in individuals with type 2 diabetes associated with CVD and DKD. Journal Diabetes Technology & Therapeutics
20-Mar-2025 The Universitat Jaume I is promoting an innovative nanotechnology project to improve therapies for cancer and infectious diseases Universitat Jaume I To date, the project has successfully developed self-assembled nanoparticles capable of loading and releasing anti-cancer drugs, such as paclitaxel and camptothecin, which are used to treat various types of tumours. Positive results have also been achieved in integrating photosensitizers like rose bengal, which, when activated by light, target cancer cells in photodynamic therapy. Journal Colloids and Surfaces B Biointerfaces Funder Ministerio de Ciencia, Innovación y Universidades, Agencia Estatal de Investigación, FEDER-UE
20-Mar-2025 Diacylglycerol O-acyltransferase 2, a novel target of flavivirus NS2B3 protease, promotes zika virus replication by regulating lipid droplet formation Research Recently, researchers in Dr. Chao Liu and Dr. Ping Zhang's team of Sun Yat-sen University identified a novel target of flavivirus protease NS2B3—diacylglycerol O-acyltransferase 2 (DGAT2), a key rate-limiting enzyme catalyzing the final step of triglyceride biosynthesis, as a Zika virus (ZIKV) dependency factor. Journal Research Funder National Natural Science Foundation of China, Natural Science Foundation of Guangdong Province, Guangzhou Municipal Science and Technology Program key projects
