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Updates every hour. Last Updated: 12-Jan-2026 18:11 ET (12-Jan-2026 23:11 GMT/UTC)
Zhejiang University analysis maps the burden of acute-on-chronic liver failure in compensated liver disease
Chinese Medical Journals Publishing House Co., Ltd.According to a new meta-analysis, acute-on-chronic liver failure (ACLF) can develop even in patients with previously compensated liver disease and is associated with a high risk of death. Reviewing studies published over the past decade, researchers found that short-term mortality remains high, despite shifts in underlying causes, with alcohol-related liver disease increasingly replacing viral hepatitis. The findings underscore the need for stronger prevention efforts and improved clinical management.
- Journal
- Portal Hypertension & Cirrhosis
- Funder
- National Key Research and Development Program of China, National Natural Science Foundation of China, Fundamental Research Funds for the Central Universities, Medical and Health Research Project of Zhejiang Province
Perfectionism and competitive sport increase the risk of exercise addiction, study finds
Universidad Miguel Hernandez de ElcheUsing artificial intelligence, researchers analyzed psychological and behavioral data from over 1,000 young adults to identify predictors of exercise addiction. Published in Addictive Behaviors, this study from UMH and ISABIAL highlights perfectionism and competition level as the strongest risk factors, paving the way for early detection and preventive strategies.
- Journal
- Addictive Behaviors
- Funder
- Plan Nacional sobre Drogas
IL1RA+ myeloid-derived suppressor cells activate epithelial-mesenchymal transition to facilitate lymphatic and hepatic metastasis in pancreatic ductal carcinoma
Xia & He Publishing Inc.- Journal
- Journal of Clinical and Translational Hepatology
Centromere protein I, a cell cycle checkpoint gene, accelerates tumor progression via the hippo pathway and mediates immune escape in hepatocellular carcinoma
Xia & He Publishing Inc.Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma (HCC). However, their precise roles and underlying mechanisms remain insufficiently characterized and require further investigation. This study aimed to explore the prognostic significance of CCCRGs in HCC, and to investigate the mechanism by which they promote the progression of HCC.
- Journal
- Journal of Clinical and Translational Hepatology
Biopsychosocial impact of multiple sclerosis in Omani patients: a multicenter comparative study
Sultan Qaboos UniversityAlthough the Sultanate of Oman has a relatively low prevalence of MS (15 cases per 100,000 people) compared to other Gulf countries, understanding the psychological, cognitive, and social burdens linked to the disease in the local context is of critical importance, especially given the increasing worldwide awareness of its impact on cognition and mental health. The disease affects vital cognitive functions in a patient’s life, such as attention, memory, and processing speed, which negatively impact their independence and quality of life.
From this standpoint, Prof. Samir Al-Adawi, from the Department of Behavioural Medicine at the College of Medicine and Health Sciences, led a research team on a multi-centre study involving clinically stable MS patients at Khawlah Hospital and Sultan Qaboos University Hospital – two of the leading neurology centres in the Sultanate of Oman.
Modulator-free light control via computational beam shaping
KeAi Communications Co., Ltd.- Funder
- Technology Innovation Leading Program of Shaanxi, National Natural Science Foundation of China
Decoding a tree genome to unlock terpenoid-based disease resistance
Nanjing Agricultural University The Academy of Science- Journal
- Horticulture Research
A hormone switch that quietly lowers vitamin C in developing fruit
Nanjing Agricultural University The Academy of Science- Journal
- Horticulture Research
How roses rapidly recover from dehydration stress
Nanjing Agricultural University The Academy of ScienceWater deficit during flowering can severely disrupt petal expansion, water uptake, and reproductive success, yet many plants are able to recover rapidly once water becomes available again.
- Journal
- Horticulture Research