Neuroblastoma remains one of the most unpredictable childhood cancers, ranging from tumors that regress without treatment to aggressive disease that resists intensive therapy. 

Hepatitis B virus (HBV) infection and hepatitis C virus (HCV) infection are among the leading causes of chronic liver diseases worldwide. Through the same transmission routes, HBV/HCV coinfection is widespread and aggravates liver damage. In this study, we aimed to assess the safety and efficacy of sofosbuvir/velpatasvir (SOF/VEL) and the pre-treatment of tenofovir alafenamide fumarate (TAF) on HBV reactivation in HBV/HCV coinfected patients.

In Canada, wealth inequality between women and men remains largely invisible because it is difficult to measure. Most data are collected at the household level, obscuring disparities between individuals within couples. 

Research led by Maude Pugliese, Professor at the Institut national de la recherche scientifique (INRS) and Canada Research Chair in Family Financial Experiences and Wealth Inequality, sheds new light on these disparities by providing the first-ever estimate of individual wealth among Canadians. 

This cross-sectional study, published in Eye & ENT Research, investigated the knowledge, attitudes and practices regarding contact lens (CL) use among students at the College of Health Sciences, University of Ghana. A total of 236 participants were enrolled via convenience sampling. The results revealed a striking mismatch: while nearly all students were aware of contact lenses, only a small proportion possessed adequate knowledge of standard care and usage, and the overall CL wearing rate was very low. Educational level was significantly associated with contact lens acceptability.

Osaka Metropolitan University researchers fabricated FeCoNi, CrFeCoNi, and CrMnFeCoNi submicrometer particles via laser ablation in liquid using subnanosecond laser pulses at 355, 532, and 1064 nm in water. 

A research team has developed hierarchical ZSM-5 zeolite catalysts whose pore structure and acidity can be adjusted through a simple one-pot synthesis, enabling longer-lasting conversion of plastic waste into gasoline-range liquids and valuable aromatic chemicals. 

Multitasking while walking – be it mentally drafting a grocery list or replying to a text message on a phone—is simply second nature to many. For stroke survivors with weakened mobility and cognitive capabilities, however, this common practice of “dual-task walking”, can present a formidable challenge. A research team at The Hong Kong Polytechnic University (PolyU) that pioneered early studies on dual-task walking and fall risk in post-stroke individuals has conducted a follow-up study, which reveals that the interaction of cognitive task type and complexity can influence the degree and pattern of “dual-task interference” (DTI), resulting in a slip in physical and mental performance. The findings offer valuable clinical implications for the design of dual-task assessment and training for stroke rehabilitation.

A new review highlights the growing importance of miR-23b, a small but powerful regulator of gene expression, in shaping the development and progression of a wide range of cancers. This molecule, part of the broader family of microRNAs, is increasingly recognised for its complex and sometimes contrasting influence on tumor behaviour, offering fresh perspectives on how cancer can be better understood and managed.